Consistent and reproducible application of microneedles.

uPRAX aims to accelerate the transition of microneedles from a research environment into real world, lifesaving solutions. With a size of less than 1 mm, they have proved to be more effective and less intrusive compared to many conventional methods of drug administration; great breakthrough innovations are being achieved around the world every day. The introduction of a standardised application procedure for end users is now begging for attention.

Control Impact Velocity & Pressing Force

Precise control of application parameters for high quality results. The velocity at impact can be set from 25 to 140 cm/sec in steps of 1 cm/sec. The force of application can also be set from 1N to 50N in steps of 1N.

Universal & Convenient

Using microneedle arrays with a specific size or shape? The applicator end-cap can be customized to serve specific needs. The microneedle mounts are also available in many different sizes and can be replaced quickly.

Precise Adjustment

A precisely adjustable microneedle mount will accommodate different types of microneedle arrays. The height can be adjusted by rotation of the end cap, allowing for fractional adjustments.

More Information?

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Associated Publications

de Groot AM, Platteel ACM, Kuijt N, van Kooten PJS, Vos PJ, Sijts AJAM and van der Maaden K (2017) Nanoporous Microneedle Arrays Effectively Induce Antibody Responses against Diphtheria and Tetanus Toxoid. Front. Immunol. 8:1789. doi: 10.3389/fimmu.2017.01789
K. van der Maaden et al., Hollow microneedle-mediated micro-injections of a liposomal HPV E743-63 synthetic long peptide vaccine for efficient induction of cytotoxic and T-helper responses, 269 (2017), pages 347-354
P. Schipper et al., Diphtheria toxoid and N-trimethyl chitosan layer-by-layer coated pHsensitive microneedles induce potent immune responses upon dermal vaccination in mice, Journal of controlled release, 262 (2017), pages 28-36